PARIS – Imagine Optic, French manufacturer of wavefront metrology and adaptive optics technology, has been entrusted with the leadership of MICADO (MICroscopy with ADaptive Optics), a three-year project that aims to develop new technology using adaptive optics for detecting and treating neurological disorders.
Financed by France's National Research Agency, the MICADO project will gather Imagine Optic (Orsay, France) and researchers from the Industrial Physics and Chemistry Higher Educational Institution (ESPCI), the Neurobiology Laboratory at the Normal Superior School (ENS) and the Laboratory of Optics and Biosciences (LOB).
A key objective of the consortium is to develop an all-new wavefront sensor, dubbed Optical Coherence Interferometer (OCI), that will complement Imagine Optic's HASO wavefront sensor. Scientists said OCI would have to be able to differentiate between the light reflected by the specified target and errant light reflected back that confuses other devices.
Commenting on the technology emanating from this collaboration, Xavier Levecq, team leader at Imagine Optic, declared: “Certain technologies, including confocal scanning microscopes, are not suitable for in vivo deep-tissue imaging because sufficiently amplifying the imaging source inevitably causes damage to the specimen. Using adaptive optics to enhance Optical Coherence Tomography (OCT) and multi-photon microscopes for subcellular deep-tissue bioimaging will enable us to dramatically improve image quality at depths of several hundred microns without damaging the living tissue.”