Moore's Law has many obstacles, some expressed by fundamental laws of nature (column 1, engineering), but it is also at the mercy of the other factors on the top row, some of which are not as limiting as some think. (Source: Igor Markov)
While we could probably improve current manufacturing techniques, i personally set my eyes on one of the crazy options promising orders of magnitude improvment: Quantum computing, Optical computing(like optalysys does) , Analog brain like computing, etc.
The first problem is that Moore's law is not a law, but only an observation. We have reduced the cost of integrated circuits over the years and we will continue to do that with many inovations. But there is no guarantee that it will continue forever and we all knew that.