Great article, as this is a difficult subject. At Stellamar we are trying to tackle this problem as well, but by essentially creating analog from the digital library. We have done this with an ADC and are working towards some of the other analog components. www.stellamar.com
I like that Calibre can do some checking of analog layout rules, that helps save time and reduce spins. What I get more excited about is when you create an analog layout compiler that is Correct By Construction that takes into account these analog rules and follows them.