I would have phrased a 5th challenge for the IC's: it is the challenge of developing applications IC's (as opposed to application specific IC's) because of the obvious reason: the falling-off the cliff statistics for new ASIC starts!
So the challenge is rather a hybrid of 1, 2 & 3: to design a low-cost application using today's and yesterday's technology for newer applications. I am sure we will begin to see a new breed of 'ASIC' companies that leverage this idea.
Power consumption is one of the biggest problem of today's electronics no matter from which point u see. Telecommunication companies already started an innovation under Greentouch.org. Why not having similar thinking for chip vendors, producers, foundries.
"Samsung announced the development of a 1-Gbit DRAM with a 512-pin wide I/O interface intended for mobile applications"
Wow, this is really good news. Does it mean that the mobile storage capability will go up significantly in near future ?