Place a diode or series resistance up stream so if VCC is lost the super cap charge will not just discharge back into the powersupply failure path. Place diodes near sink rather than source add as many as nodes need holdup protection.
Use synchronous rectifier if voltage drop cannot be tolerated. gate charge terminated when input voltage is removed.
These are great for powering up the circuitry that logs power failure events in advanced power supply designs. These circuits need to stay powered until the log data is stored in a small flash memory so a smaller supercap is perfect.
It is just amazing to know how fast the technology is changing. In my college days, to think of Capacitor with more than a farad capacity would be like thinking of a room-size jumbo capacitor. This super capacitor technology has brought it to a coin size. These devices will surely replace all those batteries used for long life battery storage. And the EVs with super capacitors can be recharged in much less time than is required to fill the gasoline.