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pip_010
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re: Developing the world’s first real-time 3D OCT medical imaging system
pip_010   4/27/2011 10:11:51 AM
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well mri is 3D volume, not surface ! also 7T-mri can provide amazing detail with resolution : fraction of the millimeter in voxel size. anatomical scans do not require toxic fluids for contrast etc. and it is noninvasive and safe. bad sides : digestive and respiratory systems are notoriously hard in MRI, though SWIFT seems to mitigate the issue. real-time is challenging due to immense post-processing, though using GPU and distributed-cluster should be a viable option for MRI too.

SpeedEvil
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re: Developing the world’s first real-time 3D OCT medical imaging system
SpeedEvil   5/2/2011 5:29:30 PM
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MRI is great. MRI is also hideously expensive. OCT is potentially a lot cheaper than MRI, with faster scanning, but it does have severe limitations as to the depth of objects it can sense. It's another tool in the arsenal, not a magic bullet.

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   5/2/2011 10:35:58 PM
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Agreed with SpeedEvil: it is an exciting but largely complementary technology to MRI or PET...I am editing a book on medical imaging for Wiley, looking for someone to write a chapter on OCT, if interested pls email: kris.iniewski@gmail.com, Kris

agk
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re: Developing the world’s first real-time 3D OCT medical imaging system
agk   6/21/2011 7:50:30 AM
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Hi iniewski i am interested to write a chapter on this. I will refer to various articles on this topic and prepare for you. Will it be allright

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   6/21/2011 2:43:59 PM
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Hi agk, great, pls email me at kris.iniewski@gmail.com

solarpower44
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re: Developing the world’s first real-time 3D OCT medical imaging system
solarpower44   5/5/2011 7:54:11 PM
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This is not true. This is not the first real-time OCT. Too bad they don't cite other works. for example: Graphics Processing Unit Accelerated Non-uniform fast Fourier transform for ultrahigh-speed, real-time Fourier-domain OCT,” Opt. Exp., vol. 18, Iss. 22, pp. 23472-23487, Oct., 2010 Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system,” Optics Express, Vol. 18, Issue 11, pp. 11772-11784, 2010

particle60
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re: Developing the world’s first real-time 3D OCT medical imaging system
particle60   5/19/2011 7:18:38 AM
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I checked the works cited by solarpower44 because I got interested in. Although they actually showed some real-time OCT, I think it is insufficient for MEDICAL IMAGING both in the image size and the image penetration depth. It seems this work's designs fit a bit better to target medical use as the title shows.

Benchuchu
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re: Developing the world’s first real-time 3D OCT medical imaging system
Benchuchu   6/21/2011 3:08:11 AM
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This work is surely no better than the examples given by solarpower44, because of the physical/optical feature of OCT imaging itself. For OCT imaging, which is limited by the scattering of tissue itself, the imaging penetration depth is up to 1~2mm for normal biological tissue and may be up to 10mm for ophthalmological structures like cornea. The imaging size mentioned by particle60, which called lateral scanning range in OCT, is just determined by the number of A-scans in one volume, which is not related to the imaging processing part. Overall, OCT is kind of novel and upcoming imaging modality, which high resolution but shallower imaging depth compared to US or CT or MRI. I think the most powerful field for OCT is the ophthalmology applications, since eye itself is the most transparent part within the body.

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   6/21/2011 5:04:51 AM
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To @Benchuchu, interesting comments. I am editing a book on medical imaging for Wiley and planning to add OCT to standard modalities (MRI, US, CT etc). Would you be interested in contributing a chapter? kris.iniewski@gmail.com

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   5/19/2011 1:41:09 PM
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To @particle60: what is the image penetration depth? Kris

particle60
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re: Developing the world’s first real-time 3D OCT medical imaging system
particle60   5/23/2011 11:13:55 PM
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Hi, The image penetration depth is the length of actually acquired image in the direction of depth from the surface.

Benchuchu
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re: Developing the world’s first real-time 3D OCT medical imaging system
Benchuchu   6/21/2011 3:00:46 AM
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I strongly agree with solarpower44. The FIRST realtime 3D (or 4D)OCT system was developed by the group at Johns Hopkins using GPU for both OCT image reconstruction (A-scan processing)and volume rendering. While this work uses FPGA for reconstruction and GPU volume rendering. The FPGA method has also been tried before [1,2]. Personally I prefer the GPU method with CUDA since it's the most cost effective approach. The FPGA module should also realize the function but it would cost much more money than a regular GPU. [1] T. E. Ustun, N. V. Iftimia, R. D. Ferguson, and D. X. Hammer, “Real-time processing for Fourier domain optical coherence tomography using a field programmable gate array,” Review of Scientific Instruments 79, 114301 (2008). [2] A. E. Desjardins, B. J. Vakoc, M. J. Suter, S. H. Yun, G. J. Tearney, B. E. Bouma, “Real-time FPGA processing for high-speed optical frequency domain imaging,” IEEE Transactions on Medical Imaging 28, 1468-1472 (2009).

agk
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re: Developing the world’s first real-time 3D OCT medical imaging system
agk   6/21/2011 8:00:40 AM
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3D OCT system by Dr Kohji works at 1310 nm center wave length and 250 narrow spectral band.They achieved OCT imaging of 60 million axial scans per second and demonstrated a 16 kHz frame rate with 1,400 A-lines per frame, a 3 mm depth range, and 23 µm resolution. With 14 bit resolution 50Mega samples per second a nearly 1GB data rate the processing is done by FPGA's with DSP. Great work and results. With this no more painfull biopsys

AsicProf
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re: Developing the world’s first real-time 3D OCT medical imaging system
AsicProf   10/2/2011 2:22:34 AM
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Hi AGK, You seems to be knowledgeable in area of medical imaging. I want to know your opinion on medical imaging company , who claims to generate real time 3d images. Recently I came across a small company imaging3.com, who claims to create real time 3d image. They claim to construct 3d volumetric image of hand / skull in in real time. Their technology is not using FBP reconstruction algorithm. They basically use fluoroscopy to measure the distance reading from the surface of the targeted volume , by rotating X source 360 degree around the object.. These distance measurement eventually used to create 3d base map (volume envelope). Now once 3d base map is created, S/W just paste 2d picture on the 3d base map. This process gives a very fast construction of 3d volume image. The gantry and cart computer are synchronized on 3d base map ....ie. when user rotates the image on the computer screen ....a message is sent to gantry computer to re-scan new coordinate ....On the opposite side ...if target moves inside the gantry ....gantry computer re-scans the new view and send a message and new image to cart computer for update ... Below is the link of their technology patent. http://www.google.com/patents?id=piISAAAAEBAJ&printsec=abstract&zoom=4&source=gbs_overview_r&cad=0#v=onepage&q&f=false I am wondering whether this technology is really feasible, given that big medial imaging companies like GE, Toshiba, Philips, and Siemens could not think of this technique. I will really appreciate if you can give me your comment on this technology. AsicProf

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   10/2/2011 5:49:08 PM
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Very interesting technology, has anyone used Imaging3 products? Kris

AsicProf
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re: Developing the world’s first real-time 3D OCT medical imaging system
AsicProf   10/3/2011 4:36:27 AM
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Hi Kris, They are waiting for 510 pre-market FDA approval before they can market the product. What you think about market potential of this technology , if it works as advertised.

krisi
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re: Developing the world’s first real-time 3D OCT medical imaging system
krisi   10/3/2011 4:11:10 PM
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Hi AsicProf: Yes, it looks very promising...I will be happy to invite them to present at CMOSET conference in Vancouver in 2012 to present (I am the chair, www.cmoset.com), Kris

AsicProf
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re: Developing the world’s first real-time 3D OCT medical imaging system
AsicProf   10/4/2011 4:46:17 AM
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Hi Kris, They will be attending RSNA in Chicago in November. Hopefully by 2012 , they will get FDA approval. You can contact company CEO at dean@imaging3.com AsicProf



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