You don't need an input diode for reverse battery protection. You can use a fet. This is a no-brainer if your low-battery-voltage operating-current is above half an amp or so.
Sepic seems easier to keep rf-clean. You have to use a boost controller rather than buck but with modern ceramic caps it's fairly plain sailing.
You mentioned that no diodes are needed. I assume you were referring to flyback diodes since you have a synchronous output. However, automotive also has a reverse battery requirement which means adding a diode in the battery feed, unless the LT8610 has reverse voltage protection. This adds a diode drop at all voltages and means that the low end battery voltage is now 3.7Volts (assuming we can use a schottky diode). USB charging and data application require 5Volts. We really need a buck-boost supply.
What are the engineering and design challenges in creating successful IoT devices? These devices are usually small, resource-constrained electronics designed to sense, collect, send, and/or interpret data. Some of the devices need to be smart enough to act upon data in real time, 24/7. Are the design challenges the same as with embedded systems, but with a little developer- and IT-skills added in? What do engineers need to know? Rick Merritt talks with two experts about the tools and best options for designing IoT devices in 2016. Specifically the guests will discuss sensors, security, and lessons from IoT deployments.