Thanks for your very informative article. But with IoT, I don't see a major problem that cannot be fixed. Just like the early years of computer networking, things will improve and a standard will be revealed because the underline topic is profit. Yes, I agree that it will be challenging at first, but I don't really see a major problem that cannot be fixed in this area.
Understanding and replicating the organ-to-organ protocols is a complex subject . It is more about the chemical reactions especially organic chemical reactions.
How the role of hormones ,which are the stimulator s for these chemical interactions , affects the interrelationship is the main thing that the researchers will have to decode , digitize and program to be able to exactly simulate the organ functionality in the lab.
MIT is doing a great job here as the progress in this area will lead to speeding up of many clinical trials without the need of human or animal guinea pigs