Personally, I think 32 bits is enough for any application I'd care to run. If you need more than a few GB of memory, IMO the application is being ridiculously wasteful. But YMMV -- if some people think it's fun to debug 16-digit hexadecimal numbers, I'll quote Mr. Knightly: "I have nothing to say against it, but that they shall not choose pleasures for me."
IMO 64 bits is for mainframe operating systems. For my personal use, I prefer something... well, more personal.
As we unveil EE Times’ 2015 Silicon 60 list, journalist & Silicon 60 researcher Peter Clarke hosts a conversation on startups in the electronics industry. Panelists Dan Armbrust (investment firm Silicon Catalyst), Andrew Kau (venture capital firm Walden International), and Stan Boland (successful serial entrepreneur, former CEO of Neul, Icera) join in the live debate.