I will be designing a charger for a series stack of LiFePO4, to reach a high voltage. I plan to make individual, Isolated chargers for each sub-pack. This is for my regular day job. However, I will share my general approach, so you all can have some fun.
Might be a good idea to cover the battery before I start the design -- a refresher is in order, to avoid poofs -- although the folks at mythbusters would rather see the big bang.
I posted part of this in William's bad assumptions blog.