If you aren't already aware of them, you might like to know about Clecos: http://www.rivetsonline.com/cleco.html which are to sheet-metal working what pins are to dress-making. They're a temporary fastener to hold 2 pieces aligned together while they are drilled or riveted.
If you want a lot of holes evenly spaced, an adjustable rivet spacer is a alternative http://www.aircraftspruce.com/catalog/topages/rivspacer.php?clickkey=6495 to a sheet of perf-board, but whether the extra expense is justified would depend on how important regularity and particular spacing is.
@ca94002...thanks for that.....I could easily have expanded this to two articles with all the other tools that commenters have given. I have a leather punch and a hand reamer as you describe, so I should not have forgotten about them. But then again, if I had covered everything I probably would not have got all these comments!
What are the engineering and design challenges in creating successful IoT devices? These devices are usually small, resource-constrained electronics designed to sense, collect, send, and/or interpret data. Some of the devices need to be smart enough to act upon data in real time, 24/7. Are the design challenges the same as with embedded systems, but with a little developer- and IT-skills added in? What do engineers need to know? Rick Merritt talks with two experts about the tools and best options for designing IoT devices in 2016. Specifically the guests will discuss sensors, security, and lessons from IoT deployments.